History of the star: A small star situated near the left knee of Ophiuchus the Serpent Holder. It was the Chinese Han, an old feudal state. It sometimes shared with eta (Sabik) the title Sabik, or "Preceding One", attached to the latter star in Al Tizini's catalogue.

It was thought that this star zeta (Han), with epsilon (Yed Posterior), marked the Akkadian lunar asterism Mulu-bat, the "Man of Death"; with eta (Sabik), theta, and xi, the Persian Garafsa, or "Serpent-tamer"; with eta (Sabik), the Sogdian Bastham, "Bound", "i.e. Ophiuchus enveloped in the coils of Ophis"; and the Khorasmian Sardhiwa, the "Head of the Evil One".

Epsilon (Yed Posterior), delta (Yed Prior) with this star zeta (Han), and eta Ophiuchi (Sabik) and alpha (Unukalhai), delta, and epsilon of Serpens, constituted the Nasak al Yamaniyy, the Southern Boundary Line of the Raudah, or Pasture, which here occupied a large portion of the heavens; other stars in Ophiuchus and Hercules forming the Nasak al Shamiyyah, or Northern Boundary. 

[Star Names, Their Lore and Meaning, Richard Hinchley Allen, 1889]. 

The astrological influences of the constellation: It is said to give a passionate, blindly good-hearted, wasteful and easily seduced nature, together with little happiness, unseen dangers, enmity, strife and slander. Pliny said that it occasioned much mortality by poisoning. This constellation has also been called Aesculapius and held to rule medicines. By the Kabalists it is associated with the Hebrew letter Oin and the 16^th Tarot Trump "The Lightning Struck Tower". (Robson*).

The astrological influences given by Manilius for the constellation Ophiuchus:

When Ophiuchus, encircled by the serpent's great coils, rises he renders the forms of snakes innocuous to those born under him. They will receive snakes into the folds of their flowing robes, and will exchange kisses with these poisonous monsters and suffer no harm. [Manilius, Astronomica, 1st century AD, book 5,  p.333].

One called Ophiuchus holds apart the serpent which with its mighty spirals [gyris] and twisted body encircles his own, that so he may untie its knots and back that winds in loops. But, bending its supple neck, the serpent looks back and returns; and the other's hands slide over the loosened coils. The struggle will last for ever, since they wage it on level terms with equal powers. [Manilius, Astronomica, 1st century AD,  book 1, p.31].

Sun: Sickness, disgrace and ruin. (Robson*). 

Moon: Disgrace, ruin and ailments affecting those parts ruled by Sagittarius. (Robson*).

References

Fixed Stars and Constellations in Astrology